231 Epidemiology of alopecia areata, totalis, universalis, and ophiasis: A systematic review and meta-analysis

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Epidemiology and burden of alopecia areata: a systematic review

BACKGROUND Alopecia areata (AA) is an autoimmune disorder characterized by patches of non-scarring alopecia affecting scalp and body hair that can be psychologically devastating. AA is clinically heterogenous, and its natural history is unpredictable. There is no preventative therapy or cure. OBJECTIVE The objective of this study is to provide an evidence-based systematic review on the epidem...

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IMPORTANCE Previous studies found conflicting results as to whether atopic dermatitis (AD) is increased in patients with vitiligo and alopecia areata (AA). OBJECTIVE To compare the prevalence of AD between patients with either vitiligo or AA and those without these disorders by performing a meta-analysis of observational studies. DATA SOURCES MEDLINE, EMBASE, Cochrane Library, Google Schola...

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Alopecia areata is a common autoimmune disorder that targets hair follicles. Swarms of lymphocytes surround the basis of the follicles, inducing loss of pigmented terminal hair and subsequently inhibit further hair growth. Depending on the extent of involvement, alopecia areata can be associated with a dramatic reduction of quality of life. Currently, no targeted treatment option is available, ...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2019

ISSN: 0022-202X

DOI: 10.1016/j.jid.2019.03.307